منابع مشابه
Kinetics of DNA Unwrapping in Nucleosomes
The eukaryotic genome is organized into complex structures known as nucleosomes, which consist of DNA tightly wrapped around four pairs of proteins called histones. This structure raises questions about the accessibility of the DNA to the proteins that must bind to the DNA for key processes such as transcription and repair. Ingenious experiments in the recent past have suggested that the fluctu...
متن کاملThe Kinetics of Enzyme Mixtures
Even purified enzyme preparations are often heterogeneous. For example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. For this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. Based...
متن کاملImplications of enzyme kinetics.
Of the many examples of oscillatory kinetic behaviour known, several are briefly reviewed, including those of glycolysis, the peroxidase-oxidase reaction and oscillations in cellular calcium concentration. It is shown that simple mathematical models employing allosteric rate laws are sufficient to explain the instability of the steady state and the appearance of sustained oscillations. The cAMP...
متن کاملEnzyme kinetics at high enzyme concentration.
We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt approximately 0 for the basic enzyme reaction at high enzyme concentration. For the first time, an approximate solution for the concentrations of the reactants uniformly valid in time is reported. Numeric...
متن کاملthe kinetics of enzyme mixtures
even purified enzyme preparations are often heterogeneous. for example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. for this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. based...
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ژورنال
عنوان ژورنال: CourseSource
سال: 2020
ISSN: 2332-6530
DOI: 10.24918/cs.2020.47